The True Lab

Department of Cell Biology & Physiology

Washington University School of Medicine

Selected Publications

2009

  • Bardill JP and True HL (2009).
    Heterologous prion interactions are altered by mutations in the prion protein Rnq1p.
    J Mol Biol. Mar 23. doi:10.1016/j.jmb.2009.03.036.
  • Strawn LA, Lin CA, Tank EM, Osman MM, Simpson SA, True HL (2009).
    Mutants of the Paf1 Complex Alter Phenotypic Expression of the Yeast Prion [PSI+].
    Mol Biol Cell. Apr;20(8):2229-41. doi:10.1091/mbc.E08-08-0813
  • Tank EM, True HL (2009).
    Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates.
    PLoS Genet. Feb;5(2):e1000382. doi:10.1371/journal.pgen.1000382

2008

  • True HL, Kalastavadi T, Tank EM (2008).
    Insights into intragenic and extragenic effectors of prion propagation using chimeric prion proteins.
    Prion. Apr;2(2):45-7.
  • Kalastavadi T, True HL (2008).
    Prion protein insertional mutations increase aggregation propensity but not fiber stability.
    BMC Biochem. Mar 17;9:7. doi:10.1186/1471-2091-9-7

2007

  • Tank EM, Harris DA, Desai AA, True HL (2007).
    Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability.
    Mol Cell Biol.  Aug;27(15):5445-55. doi:10.1128/MCB.02127-06

2006

  • Strawn LA, True HL (2006).
    Deletion of RNQ1 gene reveals novel functional relationship between divergently transcribed Bik1p/CLIP-170 and Sfi1p in spindle pole body separation.
    Curr Genet. Dec;50(6):347-66. doi:10.1007/s00294-006-0098-6
  • Harris DA, True HL (2006).
    New insights into prion structure and toxicity.
    Neuron. May 4;50(3):353-7. doi:10.1016/j.neuron.2006.04.020
  • True HL (2006).
    The battle of the fold: chaperones take on prions.
    Trends Genet. Feb;22(2):110-7. doi:10.1016/j.tig.2005.12.004