The True Lab

Department of Cell Biology & Physiology

Washington University School of Medicine

Heather True

Born in Madison, WI
Raised in Green Bay, WI (yes, the frozen tundra)
B.S., University of Wisconsin – Parkside, 1992
Ph.D., University of Illinois – Urbana, 1998
Postdoc, University of Chicago, 1998-2001, and Whitehead Institute/MIT, 2001-2003
Assistant Professor, Washington University School of Medicine, 2003-2009
Associate Professor, Washington University School of Medicine, 2009-
Hope Center investigator, 2003-

Pre-WashU, see Publications tab for full list

  • True HL, Berlin I, Lindquist SL (2004). Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits. Nature. 431(7005). doi:10.1038/nature02885
  • Jensen MA, True HL, Chernoff YO, Lindquist S (2001). Molecular population genetics and evolution of a prion-like protein in Saccharomyces cerevisiae. Genetics. 159(2):527-35.
  • Brusca EM, True HL, Celander DW (2001). Novel RNA-binding properties of Pop3p support a role for eukaryotic RNase P protein subunits in substrate recognition. J Biol Chem. 276(45). doi:10.1074/jbc.M107293200
  • Causton HC, Ren B, Koh SS, Harbison CT, Kanin E, Jennings EG, Lee TI, True HL, Lander ES, Young RA (2001). Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell. 12(2):323-37.
  • True HL, Lindquist SL (2000). A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature. 407(6803):477-83. doi:10.1038/35035005
  • Celander DW, Bennett KA, Fouts DE, Seitz EA, True HL (2000). RNA challenge phages as genetic tools for study of RNA-ligand interactions. Methods Enzymol. 318:332-50.
  • True HL, Celander DW (1998). Protein components contribute to active site architecture for eukaryotic ribonuclease P. J Biol Chem. 273(13):7193-6. doi:10.1074/jbc.273.13.7193
  • Fouts DE, True HL, Celander DW (1997). Functional recognition of fragmented operator sites by R17/MS2 coat protein, a translational repressor. Nucleic Acids Res. 25(22):4464-73.
  • Fouts DE, True HL, Cengel KA, Celander DW (1997). Site-specific phosphorylation of the human immunodeficiency virus type-1 Rev protein accelerates formation of an efficient RNA-binding conformation. Biochemistry. 36(43):13256-62. doi:10.1021/bi971551d
  • Wang S, True HL, Seitz EM, Bennett KA, Fouts DE, Gardner JF, Celander DW (1997). Direct genetic selection of two classes of R17/MS2 coat proteins with altered capsid assembly properties and expanded RNA-binding activities. Nucleic Acids Res. 25(8):1649-57.
  • True HL, Celander DW (1996). Ribonuclease P of Tetrahymena thermophila. J Biol Chem. 271(28):16559-66.
  • Coleman RH, Shaffer J, True H (1996). Properties of beta-lactamase from Pseudomonas syringae. Curr Microbiol. 32(3):147-50.
Heather True